Gene: KDM5A

Alternate names for this Gene: RBBP-2|RBBP2|RBP2

Gene Summary: This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.

Gene is located in Chromosome: 12

Location in Chromosome : 12p13.33

Description of this Gene: lysine demethylase 5A

Type of Gene: protein-coding

rs7977462 in KDM5A gene and Systolic Pressure PMID 28739976 2017 Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.