Gene: KIF12

Alternate names for this Gene: -

Gene Summary: This gene encodes a member of the kinesin superfamily of microtubule-associated molecular motors with functions related to the microtubule cytosekelton. Members of this superfamily play important roles in intracellular transport and cell division. A similar protein in mouse functions in the beta cell antioxidant signaling cascade, acting as a scaffold for the transcription factor specificity protein 1 (Sp1). Mice that lack this gene exhibit beta cell oxidative stress resulting in hypoinsulinemic glucose intolerance.

Gene is located in Chromosome: 9

Location in Chromosome : 9q32

Description of this Gene: kinesin family member 12

Type of Gene: protein-coding

rs12347081 in KIF12 gene and Coronary heart disease PMID 23364394 2013 A genome-wide association study of a coronary artery disease risk variant.