Gene: KLC3

Alternate names for this Gene: KLC2|KLC2L|KLCt|KNS2B

Gene Summary: This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.32

Description of this Gene: kinesin light chain 3

Type of Gene: protein-coding

Gene: ERCC2

Alternate names for this Gene: COFS2|EM9|TFIIH|TTD|TTD1|XPD

Gene Summary: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.32

Description of this Gene: ERCC excision repair 2, TFIIH core complex helicase subunit

Type of Gene: protein-coding