Gene: KLHL10

Alternate names for this Gene: SPGF11

Gene Summary: The protein encoded by this gene belongs to the kelch repeat-containing family, and contains an N-terminal BTB/POZ domain a BACK domain and six C-terminal kelch repeats. Kelch domains are thought to form a four stranded beta-sheet blade structure that can fold into a beta-propeller domain when multiple kelch repeats are found together. Mutations in this gene have been associated with oligozoospermia in some infertile males.

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.2

Description of this Gene: kelch like family member 10

Type of Gene: protein-coding

rs8068544 in KLHL10 gene and Reticulocyte count (procedure) PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs370756367 in KLHL10 gene and SPERMATOGENIC FAILURE 11 PMID 17047026 2006 Non-invasive genetic diagnosis of male infertility using spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization.