Gene: KLK2

Alternate names for this Gene: KLK2A2|hGK-1|hK2

Gene Summary: This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.33

Description of this Gene: kallikrein related peptidase 2

Type of Gene: protein-coding