Gene: KLRG1

Alternate names for this Gene: 2F1|CLEC15A|MAFA|MAFA-2F1|MAFA-L|MAFA-LIKE

Gene Summary: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules.

Gene is located in Chromosome: 12

Location in Chromosome : 12p13.31

Description of this Gene: killer cell lectin like receptor G1

Type of Gene: protein-coding

Gene: M6PR

Alternate names for this Gene: CD-M6PR|CD-MPR|MPR 46|MPR-46|MPR46|SMPR

Gene Summary: This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.

Gene is located in Chromosome: 12

Location in Chromosome : 12p13.31

Description of this Gene: mannose-6-phosphate receptor, cation dependent

Type of Gene: protein-coding