Gene: KMT5A

Alternate names for this Gene: PR-Set7|PR/SET07|SET07|SET8|SETD8

Gene Summary: The protein encoded by this gene is a protein-lysine N-methyltransferase that can monomethylate Lys-20 of histone H4 to effect transcriptional repression of some genes. The encoded protein is required for cell proliferation and plays a role in chromatin condensation.

Gene is located in Chromosome: 12

Location in Chromosome : 12q24.31

Description of this Gene: lysine methyltransferase 5A

Type of Gene: protein-coding

rs28516750 in KMT5A gene and Serum total cholesterol measurement PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.

rs28377694 in KMT5A gene and Vital capacity PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.