Gene: LARS2

Alternate names for this Gene: HLASA|LEURS|PRLTS4|mtLeuRS

Gene Summary: This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid.

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.31

Description of this Gene: leucyl-tRNA synthetase 2, mitochondrial

Type of Gene: protein-coding

Gene: LARS2-AS1

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

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rs199589947 in LARS2;LARS2-AS1 gene and HYDROPS, LACTIC ACIDOSIS, AND SIDEROBLASTIC ANEMIA PMID 26537577 2016 LARS2 Variants Associated with Hydrops, Lactic Acidosis, Sideroblastic Anemia, and Multisystem Failure.

rs199589947 in LARS2;LARS2-AS1 gene and PERRAULT SYNDROME 4 PMID 23541342 2013 Mutations in LARS2, encoding mitochondrial leucyl-tRNA synthetase, lead to premature ovarian failure and hearing loss in Perrault syndrome.