Gene: LASP1

Alternate names for this Gene: Lasp-1|MLN50

Gene Summary: This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.

Gene is located in Chromosome: 17

Location in Chromosome : 17q12

Description of this Gene: LIM and SH3 protein 1

Type of Gene: protein-coding

rs140564516 in LASP1 gene and Impaired cognition PMID 26252872 2015 Variations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aβ1-42 Level.