Gene: LHFPL3

Alternate names for this Gene: LHFPL4

Gene Summary: This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-like gene is fused to a high-mobility group gene in a translocation-associated lipoma. A partial gene fragment named LHFPL4 corresponds to a portion of the first exon of this gene.

Gene is located in Chromosome: 7

Location in Chromosome : 7q22.2-q22.3

Description of this Gene: LHFPL tetraspan subfamily member 3

Type of Gene: protein-coding

rs2465065 in LHFPL3 gene and Arthritis, Gouty PMID 22179738 2012 Gout and type 2 diabetes have a mutual inter-dependent effect on genetic risk factors and higher incidences.

rs2385168 in LHFPL3 gene and Coronary heart disease PMID 21971053 2012 Genome-wide association study of coronary artery disease in the Japanese.

rs2465065 in LHFPL3 gene and Gout PMID 22179738 2012 Gout and type 2 diabetes have a mutual inter-dependent effect on genetic risk factors and higher incidences.

rs13234807 in LHFPL3 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

rs10953454 in LHFPL3 gene and Obesity PMID 21552555 2011 A genome-wide association study on obesity and obesity-related traits.

rs4265125 in LHFPL3 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.