Gene: LILRB3

Alternate names for this Gene: CD85A|HL9|ILT-5|ILT5|LILRA6|LIR-3|LIR3|PIR-B|PIRB

Gene Summary: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.42

Description of this Gene: leukocyte immunoglobulin like receptor B3

Type of Gene: protein-coding

Gene: LILRA6

Alternate names for this Gene: CD85b|ILT-8|ILT5|ILT8|LILRB3|LILRB6

Gene Summary:

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.42

Description of this Gene: leukocyte immunoglobulin like receptor A6

Type of Gene: protein-coding

Gene: RPS9

Alternate names for this Gene: S9

Gene Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S4P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.42

Description of this Gene: ribosomal protein S9

Type of Gene: protein-coding

rs255773 in LILRB3;LILRA6;RPS9 gene and Birth Weight PMID 31043758 2019 Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.