Gene: LIMA1

Alternate names for this Gene: EPLIN|LDLCQ8|SREBP3

Gene Summary: This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated.

Gene is located in Chromosome: 12

Location in Chromosome : 12q13.12

Description of this Gene: LIM domain and actin binding 1

Type of Gene: protein-coding

rs34245511 in LIMA1 gene and Adenocarcinoma of large intestine PMID 24737748 2014 Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

rs34245511 in LIMA1 gene and COLORECTAL CANCER, SUSCEPTIBILITY TO, 1 PMID 24737748 2014 Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

rs34245511 in LIMA1 gene and COLORECTAL CANCER, SUSCEPTIBILITY TO, 10 PMID 24737748 2014 Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

rs34245511 in LIMA1 gene and COLORECTAL CANCER, SUSCEPTIBILITY TO, 12 PMID 24737748 2014 Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

rs34245511 in LIMA1 gene and COLORECTAL CANCER, SUSCEPTIBILITY TO, 3 PMID 24737748 2014 Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

rs4883482 in LIMA1 gene and Cardiovascular Diseases PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs34245511 in LIMA1 gene and Colorectal Carcinoma PMID 24737748 2014 Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

rs34245511 in LIMA1 gene and Colorectal Neoplasms PMID 24737748 2014 Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

rs34245511 in LIMA1 gene and Malignant neoplasm of large intestine PMID 24737748 2014 Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

rs34245511 in LIMA1 gene and Malignant tumor of colon PMID 24737748 2014 Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

rs4883481 in LIMA1 gene and Systolic Pressure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs2302900 in LIMA1 gene and White Blood Cell Count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.