Gene: LINC01219

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Gene: MRPL23-AS1

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Gene: MRPL23

Alternate names for this Gene: L23MRP|RPL23|RPL23L

Gene Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11.

Gene is located in Chromosome: 11

Location in Chromosome : 11p15.5

Description of this Gene: mitochondrial ribosomal protein L23

Type of Gene: protein-coding

rs12575654 in LINC01219;MRPL23-AS1;MRPL23 gene and Alcohol consumption PMID 29912962 2018 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

rs12575654 in LINC01219;MRPL23-AS1;MRPL23 gene and Systolic Pressure PMID 29912962 2018 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.