Gene: LINC01568

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 16

Location in Chromosome : 16q22.3

Description of this Gene: long intergenic non-protein coding RNA 1568

Type of Gene: ncRNA

Gene: ZFHX3

Alternate names for this Gene: ATBF1|ATBT|C16orf47|ZFH-3|ZNF927

Gene Summary: This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 16

Location in Chromosome : 16q22.2-q22.3

Description of this Gene: zinc finger homeobox 3

Type of Gene: protein-coding

rs117934006 in LINC01568;ZFHX3 gene and Body mass index PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs12446956 in LINC01568;ZFHX3 gene and Major Depressive Disorder PMID 21042317 2012 Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned.