Gene: LOC101926934

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 6

Location in Chromosome : 6p12.3

Description of this Gene: uncharacterized LOC101926934

Type of Gene: ncRNA

Gene: SLC25A27

Alternate names for this Gene: UCP4

Gene Summary: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 6

Location in Chromosome : 6p12.3

Description of this Gene: solute carrier family 25 member 27

Type of Gene: protein-coding

rs2270450 in LOC101926934;SLC25A27 gene and Autoimmune thyroiditis PMID 25429627 2015 Identification of a Hashimoto thyroiditis susceptibility locus via a genome-wide comparison with Graves' disease.

rs2270450 in LOC101926934;SLC25A27 gene and Graves Disease PMID 25429627 2015 Identification of a Hashimoto thyroiditis susceptibility locus via a genome-wide comparison with Graves' disease.

rs2270450 in LOC101926934;SLC25A27 gene and Hashimoto Disease PMID 25429627 2015 Identification of a Hashimoto thyroiditis susceptibility locus via a genome-wide comparison with Graves' disease.