Gene: LOC101928120

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: SHC1

Alternate names for this Gene: SHC|SHCA

Gene Summary: This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1q21.3

Description of this Gene: SHC adaptor protein 1

Type of Gene: protein-coding

Gene: PYGO2

Alternate names for this Gene: 1190004M21Rik

Gene Summary:

Gene is located in Chromosome: 1

Location in Chromosome : 1q21.3

Description of this Gene: pygopus family PHD finger 2

Type of Gene: protein-coding