Gene: LOC101929200

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: ADAMTS16

Alternate names for this Gene: ADAMTS16s

Gene Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may inhibit chondrosarcoma cell proliferation and migration. This gene may regulate blood pressure.

Gene is located in Chromosome: 5

Location in Chromosome : 5p15.32

Description of this Gene: ADAM metallopeptidase with thrombospondin type 1 motif 16

Type of Gene: protein-coding

rs41524744 in LOC101929200;ADAMTS16 gene and Glaucoma, Open-Angle PMID 22428042 2012 Common variants in CDKN2B-AS1 associated with optic-nerve vulnerability of glaucoma identified by genome-wide association studies in Japanese.