Gene: LOC105370455

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: PAX9

Alternate names for this Gene: STHAG3

Gene Summary: This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. Mice lacking this gene exhibit impaired development of organs, musculature and the skeleton, including absent and abnormally developed teeth, and neonatal lethality. Mutations in the human gene are associated with selective tooth agenesis-3.

Gene is located in Chromosome: 14

Location in Chromosome : 14q13.3

Description of this Gene: paired box 9

Type of Gene: protein-coding

rs2236007 in LOC105370455;PAX9 gene and Breast Carcinoma PMID 23535729 2013 Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

PMID 29059683 2017 Association analysis identifies 65 new breast cancer risk loci.

PMID 25751625 2015 Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.

rs2236007 in LOC105370455;PAX9 gene and Malignant neoplasm of breast PMID 23535729 2013 Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

rs1555316697 in LOC105370455;PAX9 gene and Reduced number of teeth PMID 29023497 2017 Characterization of PAX9 variant P20L identified in a Japanese family with tooth agenesis.

rs104894469 in LOC105370455;PAX9 gene and Tooth Agenesis, Selective, 3 PMID 12786960 2003 Novel mutation in the paired box sequence of PAX9 gene in a sporadic form of oligodontia.

PMID 29023497 2017 Characterization of PAX9 variant P20L identified in a Japanese family with tooth agenesis.