Gene: LOC105371082

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: SOCS1

Alternate names for this Gene: CIS1|CISH1|JAB|SOCS-1|SSI-1|SSI1|TIP-3|TIP3

Gene Summary: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Gene is located in Chromosome: 16

Location in Chromosome : 16p13.13

Description of this Gene: suppressor of cytokine signaling 1

Type of Gene: protein-coding

Gene: RMI2

Alternate names for this Gene: BLAP18|C16orf75

Gene Summary: RMI2 is a component of the BLM (RECQL3; MIM 604610) complex, which plays a role in homologous recombination-dependent DNA repair and is essential for genome stability (Xu et al., 2008 [PubMed 18923082]).[supplied by OMIM, Nov 2008].

Gene is located in Chromosome: 16

Location in Chromosome : 16p13.13

Description of this Gene: RecQ mediated genome instability 2

Type of Gene: protein-coding