Gene: LOC105373166

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: CAPN9

Alternate names for this Gene: GC36|nCL-4

Gene Summary: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1q42.2

Description of this Gene: calpain 9

Type of Gene: protein-coding

rs10495300 in LOC105373166;CAPN9 gene and Thyroglobulin antibody measurement PMID 29678681 2019 Genome-wide meta-analysis identifies novel gender specific loci associated with thyroid antibodies level in Croatians.