Gene: LOC105374476

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: SLC2A9

Alternate names for this Gene: GLUT9|GLUTX|UAQTL2|URATv1

Gene Summary: This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene is located in Chromosome: 4

Location in Chromosome : 4p16.1

Description of this Gene: solute carrier family 2 member 9

Type of Gene: protein-coding

rs10011206 in LOC105374476;SLC2A9 gene and Arthritis, Gouty PMID 20884846 2010 Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.

PMID 23263486 2013 Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

PMID 21768215 2011 Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.

PMID 25646370 2016 Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes.

rs6857001 in LOC105374476;SLC2A9 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs10011206 in LOC105374476;SLC2A9 gene and Gout PMID 20884846 2010 Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.

PMID 23263486 2013 Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

PMID 21768215 2011 Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.

PMID 25646370 2016 Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes.

rs181509591 in LOC105374476;SLC2A9 gene and Hypouricemia, Renal, 2 PMID 19026395 2008 Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia.

PMID 19926891 2010 Homozygous SLC2A9 mutations cause severe renal hypouricemia.

PMID 21810765 2012 Two novel homozygous SLC2A9 mutations cause renal hypouricemia type 2.

rs10011206 in LOC105374476;SLC2A9 gene and Uric acid measurement (procedure) PMID 19503597 2009 Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.

PMID 21294900 2011 A genome-wide association study of serum uric acid in African Americans.

PMID 26902266 2016 Genome wide association study of uric acid in Indian population and interaction of identified variants with Type 2 diabetes.

PMID 22797727 2012 Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.

PMID 31207883 2019 Influence of Genetic and Non-Genetic Risk Factors for Serum Uric Acid Levels and Hyperuricemia in Mexicans.

PMID 29124443 2018 Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.

PMID 30993211 2019 Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals.

PMID 29558500 2018 Genome-wide association analysis identifies multiple loci associated with kidney disease-related traits in Korean populations.

PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.