Gene: LOC105374845

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: RNF103

Alternate names for this Gene: HKF-1|KF-1|KF1|ZFP-103|ZFP103

Gene Summary: The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene.

Gene is located in Chromosome: 2

Location in Chromosome : 2p11.2

Description of this Gene: ring finger protein 103

Type of Gene: protein-coding

Gene: RNF103-CHMP3

Alternate names for this Gene: CGI149|CHMP3|NEDF|RNF103-VPS24|VPS24|hVps24

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring RNF103 (ring finger protein 103) and CHMP3 (charged multivesicular body protein 3) genes. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product.

Gene is located in Chromosome: 2

Location in Chromosome : 2p11.2

Description of this Gene: RNF103-CHMP3 readthrough

Type of Gene: protein-coding