Gene: LOC105378083

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: LOC107986664

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: TAGAP

Alternate names for this Gene: ARHGAP47|FKSG15|IDDM21|TAGAP1

Gene Summary: This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including rheumatoid arthritis, celiac disease, and multiple sclerosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms.

Gene is located in Chromosome: 6

Location in Chromosome : 6q25.3

Description of this Gene: T cell activation RhoGTPase activating protein

Type of Gene: protein-coding

rs1738074 in LOC105378083;LOC107986664;TAGAP gene and Asthma PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs1738074 in LOC105378083;LOC107986664;TAGAP gene and Autoimmune Diseases PMID 21383967 2011 Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

rs1738074 in LOC105378083;LOC107986664;TAGAP gene and Celiac Disease PMID 18311140 2008 Newly identified genetic risk variants for celiac disease related to the immune response.

PMID 20190752 2010 Multiple common variants for celiac disease influencing immune gene expression.

PMID 24999842 2014 Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus.

rs1738074 in LOC105378083;LOC107986664;TAGAP gene and Immune System Diseases PMID 21383967 2011 Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

rs1738074 in LOC105378083;LOC107986664;TAGAP gene and Multiple Sclerosis PMID 22190364 2011 Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

PMID 21833088 2011 Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.