Gene: LOC112268143

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: ADAMTS7

Alternate names for this Gene: ADAM-TS 7|ADAM-TS7|ADAMTS-7

Gene Summary: The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease.

Gene is located in Chromosome: 15

Location in Chromosome : 15q25.1

Description of this Gene: ADAM metallopeptidase with thrombospondin type 1 motif 7

Type of Gene: protein-coding