Gene: LOC112268430

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: FN1

Alternate names for this Gene: CIG|ED-B|FINC|FN|FNZ|GFND|GFND2|LETS|MSF|SMDCF

Gene Summary: This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined.

Gene is located in Chromosome: 2

Location in Chromosome : 2q35

Description of this Gene: fibronectin 1

Type of Gene: protein-coding

rs137854487 in LOC112268430;FN1 gene and GLOMERULOPATHY WITH FIBRONECTIN DEPOSITS 2 (disorder) PMID 18268355 2008 Mutations in FN1 cause glomerulopathy with fibronectin deposits.