Gene: LOC283665

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: ALDH1A2

Alternate names for this Gene: RALDH(II)|RALDH2|RALDH2-T

Gene Summary: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

Gene is located in Chromosome: 15

Location in Chromosome : 15q21.3

Description of this Gene: aldehyde dehydrogenase 1 family member A2

Type of Gene: protein-coding

rs2464469 in LOC283665;ALDH1A2 gene and Adenocarcinoma Of Esophagus PMID 27527254 2016 Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.

rs2464469 in LOC283665;ALDH1A2 gene and Barrett Esophagus PMID 27527254 2016 Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.

rs11635486 in LOC283665;ALDH1A2 gene and Serum albumin measurement PMID 22286219 2012 Genome-wide association study identifies multiple loci influencing human serum metabolite levels.