Gene: LPGAT1
Alternate names for this Gene: FAM34A|FAM34A1|NET8
Gene Summary: This gene encodes a member of the lysophospholipid acyltransferase family. The encoded protein catalyzes the reacylation of lysophosphatidylglycerol to phosphatidylglycerol, a membrane phospholipid that is an important precursor for the synthesis of cardiolipin. Alternative splicing results in multiple transcript variants.
Gene is located in Chromosome: 1
Location in Chromosome : 1q32.3
Description of this Gene: lysophosphatidylglycerol acyltransferase 1
Type of Gene: protein-coding
rs11119805 in
LPGAT1 gene and
Fatty acid measurement
PMID 23362303 2013 Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
rs7526682 in
LPGAT1 gene and
Major Depressive Disorder
PMID 29495898 2018 Molecular Genetic Analysis Subdivided by Adversity Exposure Suggests Etiologic Heterogeneity in Major Depression.
rs11119805 in
LPGAT1 gene and
Phospholipid measurement
PMID 23362303 2013 Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.