Gene: LRFN5

Alternate names for this Gene: C14orf146|FIGLER8|SALM5

Gene Summary: This gene encodes a protein that belongs to the leucine-rich repeat and fibronectin type III domain-containing family of proteins. A similar protein in mouse, a glycosylated transmembrane protein, is thought to function in presynaptic differentiation.

Gene is located in Chromosome: 14

Location in Chromosome : 14q21.1

Description of this Gene: leucine rich repeat and fibronectin type III domain containing 5

Type of Gene: protein-coding

rs1900599 in LRFN5 gene and Major Depressive Disorder PMID 29662059 2018 Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.

PMID 29700475 2018 Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.

rs34217772 in LRFN5 gene and Myopia PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.