Gene: LRIG1

Alternate names for this Gene: LIG-1|LIG1

Gene Summary:

Gene is located in Chromosome: 3

Location in Chromosome : 3p14.1

Description of this Gene: leucine rich repeats and immunoglobulin like domains 1

Type of Gene: protein-coding

Gene: SLC25A26

Alternate names for this Gene: COXPD28|SAMC

Gene Summary: This gene is a member of the mitochondrial carrier family which includes nuclear-encoded transporters localized on the inner mitochondrial membranes. Members of the family transport important small molecules across the mitochondrial inner membrane. This protein is involved in the transport of S-adenosylmethionine (SAM) into the mitochondria. Mutations in this gene are associated with combined oxidative phosphorylation deficiency 28. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene is located in Chromosome: 3

Location in Chromosome : 3p14.1

Description of this Gene: solute carrier family 25 member 26

Type of Gene: protein-coding

rs2306272 in LRIG1;SLC25A26 gene and Atrial Fibrillation PMID 29892015 2018 Multi-ethnic genome-wide association study for atrial fibrillation.

rs17831815 in LRIG1;SLC25A26 gene and Systolic Pressure PMID 27841878 2017 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.

PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.