Gene: LRRC31

Alternate names for this Gene: HEL-S-293

Gene Summary:

Gene is located in Chromosome: 3

Location in Chromosome : 3q26.2

Description of this Gene: leucine rich repeat containing 31

Type of Gene: protein-coding

rs1920116 in LRRC31 gene and Central Nervous System Neoplasms PMID 24908248 2014 Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.

rs1920116 in LRRC31 gene and Glioma PMID 24908248 2014 Here we identify a new SNP associated with glioma risk, rs1920116 (near TERC), that reached genome-wide significance (Pcombined = 8.3 × 10(-9)) in a meta-analysis of genome-wide association studies (GWAS) of high-grade glioma and replication data (1,644 cases and 7,736 controls).

rs11709840 in LRRC31 gene and Multiple Myeloma PMID 23955597 2013 Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.