Gene: LRRC53

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: FPGT-TNNI3K

Alternate names for this Gene: CARK|TNNI3K

Gene Summary: This locus represents naturally occurring read-through transcription from the neighboring fucose-1-phosphate guanylyltransferase (FPGT) and TNNI3 interacting kinase (TNNI3K) genes. Alternative splicing results in multiple transcript variants that are composed of in-frame exons from each individual gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1p31.1

Description of this Gene: FPGT-TNNI3K readthrough

Type of Gene: protein-coding

Gene: TNNI3K

Alternate names for this Gene: CARK|CCDD

Gene Summary: This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology.

Gene is located in Chromosome: 1

Location in Chromosome : 1p31.1

Description of this Gene: TNNI3 interacting kinase

Type of Gene: protein-coding

rs1040070 in LRRC53;FPGT-TNNI3K;TNNI3K gene and Age at menarche PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

rs1514174 in LRRC53;FPGT-TNNI3K;TNNI3K gene and Body mass index PMID 26426971 2015 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

PMID 28448500 2017 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

rs1040070 in LRRC53;FPGT-TNNI3K;TNNI3K gene and Obesity PMID 22484627 2012 A genome-wide association meta-analysis identifies new childhood obesity loci.

PMID 23563607 2013 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.

rs7551507 in LRRC53;FPGT-TNNI3K;TNNI3K gene and Physical Activity Measurement PMID 28448500 2017 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.