Gene: LRRIQ4

Alternate names for this Gene: LRRC64

Gene Summary:

Gene is located in Chromosome: 3

Location in Chromosome : 3q26.2

Description of this Gene: leucine rich repeats and IQ motif containing 4

Type of Gene: protein-coding

rs10936602 in LRRIQ4 gene and Multiple Myeloma PMID 23955597 2013 Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.

rs10936602 in LRRIQ4 gene and Renal Cell Carcinoma PMID 28598434 2017 We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10<sup>-10</sup>), 3p22.1 (rs67311347, P=2.5 × 10<sup>-8</sup>), 3q26.2 (rs10936602, P=8.8 × 10<sup>-9</sup>), 8p21.3 (rs2241261, P=5.8 × 10<sup>-9</sup>), 10q24.33-q25.1 (rs11813268, P=3.9 × 10<sup>-8</sup>), 11q22.3 (rs74911261, P=2.1 × 10<sup>-10</sup>) and 14q24.2 (rs4903064, P=2.2 × 10<sup>-24</sup>).