Gene: LSAMP

Alternate names for this Gene: IGLON3|LAMP

Gene Summary: This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

Gene is located in Chromosome: 3

Location in Chromosome : 3q13.31

Description of this Gene: limbic system associated membrane protein

Type of Gene: protein-coding

rs4378954 in LSAMP gene and Adenocarcinoma of large intestine PMID 26621817 2015 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

rs17646258 in LSAMP gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

PMID 29875488 2018 Genomic atlas of the human plasma proteome.

rs4378954 in LSAMP gene and COLORECTAL CANCER, SUSCEPTIBILITY TO, 1 PMID 26621817 2015 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

rs4378954 in LSAMP gene and COLORECTAL CANCER, SUSCEPTIBILITY TO, 10 PMID 26621817 2015 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

rs4378954 in LSAMP gene and COLORECTAL CANCER, SUSCEPTIBILITY TO, 12 PMID 26621817 2015 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

rs4378954 in LSAMP gene and COLORECTAL CANCER, SUSCEPTIBILITY TO, 3 PMID 26621817 2015 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

rs4378954 in LSAMP gene and Colorectal Carcinoma PMID 26621817 2015 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

rs4378954 in LSAMP gene and Colorectal Neoplasms PMID 26621817 2015 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

rs4378954 in LSAMP gene and Endometrial Neoplasms PMID 26621817 2015 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

rs4378954 in LSAMP gene and Malignant neoplasm of large intestine PMID 26621817 2015 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

rs13325108 in LSAMP gene and Malignant neoplasm of prostate PMID 21743057 2011 Genome-wide association study identifies new prostate cancer susceptibility loci.

rs4378954 in LSAMP gene and Malignant tumor of colon PMID 26621817 2015 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

rs9858874 in LSAMP gene and White Blood Cell Count procedure PMID 21738479 2011 Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).