Gene: LSM1

Alternate names for this Gene: CASM|YJL124C

Gene Summary: This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Gene is located in Chromosome: 8

Location in Chromosome : 8p11.23

Description of this Gene: LSM1 homolog, mRNA degradation associated

Type of Gene: protein-coding

Gene: LOC105379382

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rs5891007 in LSM1;LOC105379382 gene and Schizophrenia PMID 28991256 2017 Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.