Gene: LSM2

Alternate names for this Gene: C6orf28|G7B|YBL026W|snRNP

Gene Summary: This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.33

Description of this Gene: LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated

Type of Gene: protein-coding

Gene: VARS1

Alternate names for this Gene: G7A|NDMSCA|VARS|VARS2

Gene Summary: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.33

Description of this Gene: valyl-tRNA synthetase 1

Type of Gene: protein-coding

rs480092 in LSM2;VARS1 gene and Diabetes Mellitus, Insulin-Dependent PMID 17632545 2007 A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.