Gene: LUC7L3

Alternate names for this Gene: CRA|CREAP-1|CROP|LUC7A|OA48-18|hLuc7A

Gene Summary: This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.33

Description of this Gene: LUC7 like 3 pre-mRNA splicing factor

Type of Gene: protein-coding

rs144210385 in LUC7L3 gene and Kidney Failure, Chronic PMID 31178898 2019 Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study.