Gene: LY6G6F

Alternate names for this Gene: C6orf21|G6f|LY6G6|LY6G6D|NG32

Gene Summary: The human G6f protein is a type I transmembrane protein belonging to the immunoglobin (Ig) superfamily, which is comprised of cell-surface proteins involved in the immune system and cellular recognition (de Vet et al., 2003 [PubMed 12852788]).[supplied by OMIM, Mar 2008]. ##Evidence-Data-START## Transcript exon combination :: BC137212.1, KU253635.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2149004 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000375832.5/ ENSP00000364992.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.33

Description of this Gene: lymphocyte antigen 6 family member G6F

Type of Gene: protein-coding

Gene: LY6G6F-LY6G6D

Alternate names for this Gene: G6F-LY6G6D|MEGT-1|MEGT1

Gene Summary: This locus represents naturally occurring readthrough transcription between the neighboring LY6G6F (lymphocyte antigen 6 family member G6F) and LY6G6D (lymphocyte antigen 6 family member G6D) genes on chromosome 6. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.33

Description of this Gene: LY6G6F-LY6G6D readthrough

Type of Gene: protein-coding

Gene: LY6G6D

Alternate names for this Gene: C6orf23|G6D|LY6-D|MEGT1|NG25

Gene Summary: LY6G6D belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Apr 2009]. ##Evidence-Data-START## Transcript exon combination :: AJ315535.1, BC125138.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.33

Description of this Gene: lymphocyte antigen 6 family member G6D

Type of Gene: protein-coding