Gene: LYZL2

Alternate names for this Gene: LYZD2

Gene Summary: Lysozymes (see LYZ; MIM 153450), especially C-type lysozymes, are well-recognized bacteriolytic factors widely distributed in the animal kingdom and play a mainly protective role in host defense. LYZL2 is a member of a family of lysozyme-like genes (Zhang et al., 2005 [PubMed 16014814]).[supplied by OMIM, Apr 2009]. CCDS Note: The coding region has been updated to start at a downstream in-frame start codon that is supported by conservation data. ##Evidence-Data-START## Transcript exon combination :: BC066294.1, AF139543.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved MANE Ensembl match :: ENST00000647634.2/ ENSP00000497408.1 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END##

Gene is located in Chromosome: 10

Location in Chromosome : 10p11.23

Description of this Gene: lysozyme like 2

Type of Gene: protein-coding

rs399593 in LYZL2 gene and Dental caries PMID 23064961 2013 GWAS of dental caries patterns in the permanent dentition.