Gene: MAP1LC3A

Alternate names for this Gene: ATG8E|LC3|LC3A|MAP1ALC3|MAP1BLC3

Gene Summary: MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.

Gene is located in Chromosome: 20

Location in Chromosome : 20q11.22

Description of this Gene: microtubule associated protein 1 light chain 3 alpha

Type of Gene: protein-coding

rs6088521 in MAP1LC3A gene and Protein C antigen measurement PMID 20802025 2010 Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study.

rs6088521 in MAP1LC3A gene and Protein C measurement PMID 20802025 2010 Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study.

rs6058078 in MAP1LC3A gene and Smoking PMID 30643258 2019 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.