Gene: MAP3K11

Alternate names for this Gene: MEKK11|MLK-3|MLK3|PTK1|SPRK

Gene Summary: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.

Gene is located in Chromosome: 11

Location in Chromosome : 11q13.1

Description of this Gene: mitogen-activated protein kinase kinase kinase 11

Type of Gene: protein-coding

Gene: PCNX3

Alternate names for this Gene: PCNXL3

Gene Summary:

Gene is located in Chromosome: 11

Location in Chromosome : 11q13.1

Description of this Gene: pecanex 3

Type of Gene: protein-coding