Gene: MAP3K19

Alternate names for this Gene: RCK|YSK4

Gene Summary:

Gene is located in Chromosome: 2

Location in Chromosome : 2q21.3

Description of this Gene: mitogen-activated protein kinase kinase kinase 19

Type of Gene: protein-coding

rs4954218 in MAP3K19 gene and Corneal Topography PMID 21979947 2012 A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries.

rs61134960 in MAP3K19 gene and Finding of Mean Corpuscular Hemoglobin PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs4954218 in MAP3K19 gene and Keratoconus PMID 21979947 2012 These findings suggest SNP rs4954218, located near the RAB3GAP1 gene, previously reported to be associated with corneal malformation, is a potential susceptibility locus for keratoconus.

rs10174944 in MAP3K19 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.