Gene: MAPK6

Alternate names for this Gene: ERK3|HsT17250|PRKM6|p97MAPK

Gene Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.

Gene is located in Chromosome: 15

Location in Chromosome : 15q21.2

Description of this Gene: mitogen-activated protein kinase 6

Type of Gene: protein-coding

Gene: LOC112268150

Alternate names for this Gene:

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rs16964720 in MAPK6;LOC112268150 gene and Adolescent idiopathic scoliosis PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs16964720 in MAPK6;LOC112268150 gene and SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.