Gene: MAPK6

Alternate names for this Gene: ERK3|HsT17250|PRKM6|p97MAPK

Gene Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.

Gene is located in Chromosome: 15

Location in Chromosome : 15q21.2

Description of this Gene: mitogen-activated protein kinase 6

Type of Gene: protein-coding

rs62015197 in MAPK6 gene and Arthritis, Gouty PMID 25676789 2015 Genome-wide association study identifies ABCG2 (BCRP) as an allopurinol transporter and a determinant of drug response.

rs62015197 in MAPK6 gene and Gout PMID 25676789 2015 Genome-wide association study identifies ABCG2 (BCRP) as an allopurinol transporter and a determinant of drug response.

rs62015197 in MAPK6 gene and Uric acid measurement (procedure) PMID 25676789 2015 Genome-wide association study identifies ABCG2 (BCRP) as an allopurinol transporter and a determinant of drug response.