Gene: MARCHF10

Alternate names for this Gene: MARCH-X|MARCH10|RNF190

Gene Summary: MARCH10 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Morokuma et al., 2007 [PubMed 17604280]).[supplied by OMIM, Apr 2010].

Gene is located in Chromosome: 17

Location in Chromosome : 17q23.2

Description of this Gene: membrane associated ring-CH-type finger 10

Type of Gene: protein-coding

rs2251393 in MARCHF10 gene and Myocardial Infarction PMID 21211798 2011 Association of a polymorphism of BTN2A1 with myocardial infarction in East Asian populations.

rs2251393 in MARCHF10 gene and Sudden Cardiac Arrest PMID 21658281 2011 GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.

rs2251393 in MARCHF10 gene and Sudden Cardiac Death PMID 21658281 2011 GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.