Gene: MARCHF7

Alternate names for this Gene: AXO|AXOT|MARCH-VII|MARCH7|RNF177

Gene Summary: MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Mar 2010].

Gene is located in Chromosome: 2

Location in Chromosome : 2q24.2

Description of this Gene: membrane associated ring-CH-type finger 7

Type of Gene: protein-coding

rs148440689 in MARCHF7 gene and Platelet Count measurement PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.