Gene: MARCO

Alternate names for this Gene: SCARA2|SR-A6

Gene Summary: The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.

Gene is located in Chromosome: 2

Location in Chromosome : 2q14.2

Description of this Gene: macrophage receptor with collagenous structure

Type of Gene: protein-coding