Gene: MARS2

Alternate names for this Gene: COXPD25|MetRS|mtMetRS

Gene Summary: This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3).

Gene is located in Chromosome: 2

Location in Chromosome : 2q33.1

Description of this Gene: methionyl-tRNA synthetase 2, mitochondrial

Type of Gene: protein-coding

rs10931791 in MARS2 gene and Allergic Reaction PMID 23817569 2013 A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.