Gene: MBOAT7

Alternate names for this Gene: BB1|LENG4|LPIAT|LPLAT|LRC4|MBOA7|MRT57|OACT7|hMBOA-7

Gene Summary: This gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the reacylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.42

Description of this Gene: membrane bound O-acyltransferase domain containing 7

Type of Gene: protein-coding

Gene: TSEN34

Alternate names for this Gene: LENG5|PCH2C|SEN34|SEN34L

Gene Summary: This gene encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.42

Description of this Gene: tRNA splicing endonuclease subunit 34

Type of Gene: protein-coding