Gene: MDFI

Alternate names for this Gene: I-MF|I-mfa

Gene Summary: This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.1

Description of this Gene: MyoD family inhibitor

Type of Gene: protein-coding