Gene: MDGA2

Alternate names for this Gene: MAMDC1|c14_5286

Gene Summary:

Gene is located in Chromosome: 14

Location in Chromosome : 14q21.3

Description of this Gene: MAM domain containing glycosylphosphatidylinositol anchor 2

Type of Gene: protein-coding

rs7159841 in MDGA2 gene and Blood Viscosity PMID 17903294 2007 Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.

rs4900715 in MDGA2 gene and Body mass index PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

rs12883384 in MDGA2 gene and NEUROTICISM PMID 18762592 2008 Genomewide association analysis followed by a replication study implicates a novel candidate gene for neuroticism.

rs1955811 in MDGA2 gene and Narcolepsy PMID 19629137 2009 Genome-wide association database developed in the Japanese Integrated Database Project.

rs12883384 in MDGA2 gene and Neurotic Disorders PMID 18762592 2008 Genomewide association analysis followed by a replication study implicates a novel candidate gene for neuroticism.

rs11627056 in MDGA2 gene and Polysomnography PMID 23251661 2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

rs7159841 in MDGA2 gene and Protein C antigen measurement PMID 17903294 2007 Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.

rs7159841 in MDGA2 gene and Protein C measurement PMID 17903294 2007 Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.

rs1160351 in MDGA2 gene and Psychosexual dysfunction PMID 22445761 2012 Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression.

rs17118552 in MDGA2 gene and Rheumatoid Arthritis PMID 22491018 2013 Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.

rs1160351 in MDGA2 gene and Sexual Dysfunction PMID 22445761 2012 The Cochran-Armitage trend test showed that 11 SNPs, tightly clustered in a distinct region on chromosome 14q21.3, were associated with SSRI/SNRI-induced sexual dysfunction at a genome-wide significance level after false discovery rate (FDR) correction, and the strongest SNP association was with rs1160351 (P=3.04 × 10(-7), risk ratio=2.92, 95% confidence interval (CI)=1.79-4.76).

rs11627056 in MDGA2 gene and Soluble Interleukin 6 Receptor Measurement PMID 23251661 2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

rs10459501 in MDGA2 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

rs188669819 in MDGA2 gene and response to bronchodilator PMID 26634245 2015 A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.